Endocrine Abstracts

Background and aims: People with type 1 diabetes (T1D) are increasingly suffering from overweight and at risk of developing insulin resistance (IR). IR may hamper glucose control and augment the risk of cardiovascular disease (CVD). Simultaneously, non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent in T1DM. The pathophysiology of NAFLD is linked to IR. The gold standard to assess IR is the euglycaemic clamp, an invasive and time-consuming test that ca...

Background and aims: Low levels of testosterone and non-alcoholic fatty liver disease (NAFLD) in obese men are both linked to the metabolic syndrome, but the independent association between testosterone and NAFLD needs to be elucidated. In this cross-sectional analysis the association between total testosterone (total T) and calculated free testosterone (cFT) on the one hand and NAFLD, non-alcoholic steatohepatitis (NASH) and fibrosis on the other hand was investigated in obes...